Article ID Journal Published Year Pages File Type
1923331 Acta Histochemica 2016 12 Pages PDF
Abstract
Pancreatic ductal adenocarcinoma (PDAC) is a deadly malignancy that affects nearly 50,000 patients each year. The overall 5-year survival rate for this malignancy remains the lowest of any cancer at around 7% due to limited diagnostic methods, disease aggressiveness and a lack of targeted therapeutic interventions. This review highlights the successes achieved over the past several decades as well as the significant cellular and molecular hurdles that remain in combatting this deadly disease at a translational level.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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