Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1925229 | Archives of Biochemistry and Biophysics | 2014 | 9 Pages |
Abstract
- Tryptophan dioxygenase catalyzes the first and committed step in the kynurenine pathway.
- Recent progress of the enzymatic studies of tryptophan oxidation is summarized.
- Catalytic strategies are proposed to involve in high-valent Fe intermediates.
- Peroxide reaction with the ferric enzyme is important for the enzyme reactivation.
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Authors
Jiafeng Geng, Aimin Liu,