Article ID Journal Published Year Pages File Type
1925229 Archives of Biochemistry and Biophysics 2014 9 Pages PDF
Abstract

- Tryptophan dioxygenase catalyzes the first and committed step in the kynurenine pathway.
- Recent progress of the enzymatic studies of tryptophan oxidation is summarized.
- Catalytic strategies are proposed to involve in high-valent Fe intermediates.
- Peroxide reaction with the ferric enzyme is important for the enzyme reactivation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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