| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1925435 | Archives of Biochemistry and Biophysics | 2013 | 6 Pages |
Abstract
⺠A derivative of the natural compound kakuol is active against human topoisomerase. ⺠The compound inhibits the cleavage reaction during DNA relaxation. ⺠Molecular docking shows that the compound binds near the active site.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Silvia Castelli, Sara Vieira, Ilda D'Annessa, Prafulla Katkar, Loana Musso, Sabrina Dallavalle, Alessandro Desideri,