| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1925470 | Archives of Biochemistry and Biophysics | 2013 | 11 Pages |
Abstract
⺠Oxidative stress increases the oxidation/nitration of intracellular hemoglobin (Hb). ⺠Hb is well protected by cellular antioxidative mechanisms from oxidation/nitration. ⺠Nitration of Hb is a sensitive indicator of oxidative damage of erythrocytes. ⺠Hb can be modified by 4-hydroxynonenal (HNE) in cell-free experiments. ⺠HNE-hemoglobin adducts are not detected in erythrocytes under oxidative stress.
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Authors
Wei Xiang, Volker Weisbach, Heinrich Sticht, Angela Seebahn, Julia Bussmann, Robert Zimmermann, Cord-Michael Becker,