| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1925602 | Archives of Biochemistry and Biophysics | 2012 | 9 Pages |
Abstract
⺠We review the mechanism of allosteric regulation of glucokinase by substrate glucose. ⺠We examine the structural changes from the published crystal structures. ⺠We discuss the role of conformational changes and of global and site specific dynamics. ⺠We discuss critical regions in glucokinase involved in the allosteric communication.
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Authors
Mioara Larion, Brian G. Miller,