Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1925682 | Archives of Biochemistry and Biophysics | 2011 | 7 Pages |
Abstract
⺠We model myocardial hypertrophy using thyroid hormone and isoproteranol in mice. ⺠The relationship between oxidative stress and selenoprotein expression in hearts is investigated. ⺠H2O2 and caspase-3 activity are increased, but no apparent tissue damage or apoptosis. ⺠MsrB1(Sel R), GPx3, and GPx4 are increased. ⺠GPx1, Trxrd1, and Trxrd2 expression are not changed in heart.
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Authors
FuKun W. Hoffmann, Ann S. Hashimoto, Byung Cheon Lee, Aaron H. Rose, Ralph V. Shohet, Peter R. Hoffmann,