Article ID Journal Published Year Pages File Type
1925700 Archives of Biochemistry and Biophysics 2011 8 Pages PDF
Abstract
► Stimulation of HMG-CoA lyase activity by reducing agents. ► Inter-subunit adduct formation in HMG-CoA lyase. ► Specific Cys → Ser mutations eliminate inter-subunit adducts in HMG-CoA lyase. ► HMGCL C266S/C323S heterodimer forms an inter-subunit adduct. ► Restoration of inter-subunit adducts in a double Cys → Ser HMG-CoA lyase mutant.
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