Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1925789 | Archives of Biochemistry and Biophysics | 2011 | 5 Pages |
Abstract
⺠An ordered kinetic mechanism is confirmed for human sulfotransferase 1A1. ⺠Addition of phenol activates the reaction by intercepting E-PAPS and converting it to E-PAP. ⺠Activation requires a non-sticky alcohol substrate. ⺠Analogs of the alcohol or sulfated alcohol reactants should be effective inhibitors.
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Authors
Eduard Tyapochkin, Vidya Prasanna Kumar, Paul F. Cook, Guangping Chen,