| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1925891 | Archives of Biochemistry and Biophysics | 2010 | 7 Pages |
Abstract
⺠The high levels of EGFR pY1068 and FAK pY397 were detected in U87ÎEGFR cells. ⺠The knockdown of FAK via RNAi reduced EGFR pY1068 and inhibited U87ÎEGFR cell migration. ⺠EGFRvIII formed a complex with FAK. ⺠Reduced FAK expression via RNAi caused dramatic inhibition of pERK1/2. ⺠ERK was involved in FAK-regulated U87ÎEGFR cell migration.
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Authors
Mingzhu Liu, Yong Yang, Can Wang, Lidong Sun, Chuanzhong Mei, Wantong Yao, Yonglei Liu, Yinghong Shi, Shuangjian Qiu, Jia Fan, Xiumei Cai, Xiliang Zha,