| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1925942 | Archives of Biochemistry and Biophysics | 2011 | 7 Pages |
Abstract
⺠[3H]8-OH-DPAT not only binds to intact HeLaS3 cells with high specific binding. ⺠But also it has multiple binding sites, some of which relate to uptake. ⺠[125I]RTI-55 and [3H]paroxetine bound in a saturable fashion to HeLaS3 cells. ⺠One or more of the related to 5-HT receptor subtypes was manifested in HeLaS3 cells. ⺠Radioligand binding properties varied between membrane preparation and intact cell.
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![Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [3H]8-OH-DPAT and other serotonergic ligands](/preview/png/1925942.png "First Page Preview: Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [3H]8-OH-DPAT and other serotonergic ligands")
Authors
Jin-Jye Feng, Fong-Chi Cheng, Chun-Hsiung Lin, Jiann-Wu Wei, Shiaw-Der Yang,