Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1926652 | Archives of Biochemistry and Biophysics | 2008 | 10 Pages |
Abstract
Sodium pump was the first ion pump discovered. A member of the family of active transporters that catalyze adenosine 5′-triphosphate hydrolysis by forming a phosphorylated enzyme intermediate, sodium pump couples the energy released to unequal countertransport of sodium and potassium ions. The ion gradient generated by the pump is important for a variety of secondary physiological processes ranging from metabolite transport to electrical excitation of nerve and muscle. Selected experiments relating structure to function are reviewed.
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Authors
Larry D. Faller,