Article ID Journal Published Year Pages File Type
1926818 Archives of Biochemistry and Biophysics 2008 5 Pages PDF
Abstract

The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that can provide insight into mechanisms of bone maintenance and also novel pharmacological targets to increase osteoblast differentiation and consequently bone formation.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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