Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1926818 | Archives of Biochemistry and Biophysics | 2008 | 5 Pages |
Abstract
The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that can provide insight into mechanisms of bone maintenance and also novel pharmacological targets to increase osteoblast differentiation and consequently bone formation.
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Authors
Moustapha Kassem, Basem M. Abdallah, Hamid Saeed,