Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1929036 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Ayanin diacetate as apoptotic inducer in leukemia cells. ⺠Cell death was prevented by caspase inhibitors and by the overexpression of Bcl-xL. ⺠The intrinsic and the extrinsic pathways are involved in the mechanism of action. ⺠Death receptors are up-regulated and TRAIL enhances apoptotic cell death.
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Authors
MarÃa Teresa Marrero, Sara Estévez, Gledy NegrÃn, José Quintana, Mariana López, Francisco J. Pérez, Jorge Triana, Francisco León, Francisco Estévez,