| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1929349 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠The dominant negative designs termed A-ZIPs heterodimerize with B-ZIPs. ⺠We designed a chimeric protein with two ubiquitin motifs at the N-terminal of A-ZIP. ⺠It results in degradation of B-ZIP heterodimerization partners more efficiently. ⺠This process of enhanced degradation is inhibited by proteasome inhibitor MG-132.
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Authors
Eric Rios-Doria, Raghunath Chatterjee, Jianfei Zhao, Vikas Rishi, Charles Vinson,