| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1929363 | Biochemical and Biophysical Research Communications | 2012 | 6 Pages |
Abstract
⺠A new antibody targeting acetylated K27 to K35 within APE1/Ref-1 is described. ⺠The antibody detects changes in APE1/Ref-1 acetylation status upon genotoxic insult. ⺠A cohort of triple negative breast cancer specimens was analyzed with the antibody. ⺠We report evidence of deregulation in APE1/Ref-1 acetylation in breast cancer. ⺠This is the first report analyzing APE1 acetylation in human cancers.
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Authors
Mattia Poletto, Carla Di Loreto, Daniela Marasco, Elena Poletto, Fabio Puglisi, Giuseppe Damante, Gianluca Tell,