Article ID Journal Published Year Pages File Type
1929405 Biochemical and Biophysical Research Communications 2012 5 Pages PDF
Abstract
► GDP and GTP increase accumulation of reactive oxygen species within the mitochondrial matrix. ► UCP2 KO mouse brain mitochondria demonstrate a decreased GDP effect on ROS release. ► Uncoupling proteins, presumably UCP2, may function as transporters of the superoxide anion.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Guanosine diphosphate exerts a lower effect on superoxide release from mitochondrial matrix in the brains of uncoupling protein-2 knockout mice: New evidence for a putative novel function of uncoupling proteins as superoxide anion transporters
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