Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1929731 | Biochemical and Biophysical Research Communications | 2012 | 5 Pages |
Abstract
⺠Bc-SMase requires a divalent metal ion for membrane binding. ⺠The side-edge of Bc-SMase plays an important role in membrane binding. ⺠Asn57, Glu99, and Asp100 at the side-edge are essential for the folding metal ion. ⺠The amino acid residues of the side-edge have no effect on enzymatic activity.
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Authors
Masataka Oda, Masaya Takahashi, Hideaki Tsuge, Masahiro Nagahama, Jun Sakurai,