Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1929891 | Biochemical and Biophysical Research Communications | 2012 | 7 Pages |
Abstract
⺠Thromboxane synthase (TXAS) mediates visfatin-induced IL-8 induction and angiogenesis. ⺠Visfatin induces the expression of TXAS and release of TXA2 in endothelial cells. ⺠Upregulation of TXAS by visfatin mediates endothelial IL-8 production. ⺠Blockade of TXAS-dependent IL-8 production inhibits visfatin-induced angiogenesis.
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Authors
Su-Ryun Kim, Yun-Hoa Jung, Hyun-Joo Park, Mi-Kyoung Kim, Joo-Won Jeong, Hye-Ock Jang, Il Yun, Soo-Kyung Bae, Moon-Kyoung Bae,