Article ID Journal Published Year Pages File Type
1929891 Biochemical and Biophysical Research Communications 2012 7 Pages PDF
Abstract
► Thromboxane synthase (TXAS) mediates visfatin-induced IL-8 induction and angiogenesis. ► Visfatin induces the expression of TXAS and release of TXA2 in endothelial cells. ► Upregulation of TXAS by visfatin mediates endothelial IL-8 production. ► Blockade of TXAS-dependent IL-8 production inhibits visfatin-induced angiogenesis.
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