| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1929942 | Biochemical and Biophysical Research Communications | 2011 | 4 Pages |
Abstract
⺠The substrate of ABCC6 preventing soft tissue calcification is not known. ⺠It was proposed that vitamin K3-glutathione conjugate is the physiological substrate. ⺠We tested VK3GS transport by several assay systems. ⺠We found that this conjugate is not a substrate of ABCC6. ⺠Vitamin K3-glutathione conjugate may not prevent pseudoxanthoma-related symptoms.
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Authors
Krisztina Fülöp, Qiujie Jiang, Koen v.d. Wetering, Viola Pomozi, Pál T. Szabó, Tamás Arányi, Balázs Sarkadi, Piet Borst, Jouni Uitto, András Váradi,