| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1929996 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠We tested the role of PRC1 in the granulocytic differentiation of human APL cells. ⺠PCGF2 expression was reduced during ATRA-mediated differentiation of HL-60 cells. ⺠PCGF2 knockdown induced differentiation of HL-60 cells via de-repression of HOXA7. ⺠Direct binding of Pcgf2 protein to HOXA7 chromatin was reduced by PCGF2 knockdown. ⺠PCGF2 plays a negative role in the granulocytic differentiation of human HL-60 cells.
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Authors
Sungsin Jo, Hongki Lee, Sojin Kim, Eun Mi Hwang, Jae-Yong Park, Sang Soo Kang, Heekyoung Chung,