Article ID Journal Published Year Pages File Type
1930005 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► aIF5B forms maximum 5.0-6.8% irreversible dimers in solution. ► Sedimentation coefficients for monomer and dimer are 3.64 and 5.51 ± 0.29 S. ► Adding only 2% glycerol prevents dimerization. ► SAXS on aIF5B monomer gave an Rg of 37.5 ± 0.2 Å and a Dmax of ∼130 Å. ► There are universal structural differences between aIF5B and Escherichia coli IF2.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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