Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1930268 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Neutrophil extracellular traps (NETs) are pivotal for innate host defense. ⺠ROS contribute to NET formation but the active species are not identified. ⺠Singlet oxygen (1O2) scavengers inhibited Nox-dependent NET formation. ⺠1O2 itself could make NETs independent of Nox activation. ⺠These results indicate that 1O2 is essential for NET formation.
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Authors
Yoko Nishinaka, Toshiyuki Arai, Souichi Adachi, Akifumi Takaori-Kondo, Kouhei Yamashita,