| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1930405 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠We focused on the interaction between SR-A and TLR4 signaling in this study. ⺠SR-A deletion promoted NFκB activation in macrophages in septic model mouse. ⺠SR-A suppresses both MyD88-dependent and -independent TLR4 signaling in vitro. ⺠SR-A clears LPS binding to TLR4 which resulting in the suppression of TLR4 signals.
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Authors
Koji Ohnishi, Yoshihiro Komohara, Yukio Fujiwara, Kenichi Takemura, XiaoFeng Lei, Takenobu Nakagawa, Naomi Sakashita, Motohiro Takeya,