Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1930502 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠PTP1B, an active player in insulin and leptin resistance. ⺠PTP1B chemical structure, substrates, activation/inactivation. ⺠The structural features of PTP1B molecule relevant to the interactions with inhibitors. ⺠The progress towards inhibitors with enhanced membrane permeability, affinity, specificity, and potency on intracellular PTP1B.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Doina Popov,