Article ID Journal Published Year Pages File Type
1930502 Biochemical and Biophysical Research Communications 2011 5 Pages PDF
Abstract
► PTP1B, an active player in insulin and leptin resistance. ► PTP1B chemical structure, substrates, activation/inactivation. ► The structural features of PTP1B molecule relevant to the interactions with inhibitors. ► The progress towards inhibitors with enhanced membrane permeability, affinity, specificity, and potency on intracellular PTP1B.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
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