Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1930569 | Biochemical and Biophysical Research Communications | 2011 | 7 Pages |
Abstract
⺠Assembly of Notch intracellular domain (NICD)-containing protein complexes is dose-dependent. ⺠MAML becomes the limiting factor for formation of canonical NICD complex when NICD level is high. ⺠There are differences in the NICD protein complexes formed by individual Notch paralogs. ⺠Among the four NICDs, Notch4 ICD shows a unique protein complex profile.
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Authors
Jianxun Han, Joan Allalunis-Turner, Michael J. Hendzel,