Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1930780 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠In this study we succeeded in developing an octaarginine modified liposome equipped with PC-SOD (R8-LP (PC-SOD)). ⺠R8-LP (PC-SOD) was taken up by cells more efficiently than PC-SOD. ⺠R8-LP (PC-SOD) has the ability to deliver PC-SOD to the cytosol efficiently. ⺠R8-LP (PC-SOD) was scavenged superoxide anions (O2-) very efficiently. ⺠The efficient cytosolic delivery by R8-LP enhances the anti-oxidant effect of PC-SOD.
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Authors
Ryo Furukawa, Yuma Yamada, Mitsuko Takenaga, Rie Igarashi, Hideyoshi Harashima,