Article ID Journal Published Year Pages File Type
1930846 Biochemical and Biophysical Research Communications 2011 6 Pages PDF
Abstract
► Four oral squamous cancer cell lines (OSCCL) were analyzed for cancer stem cells (CSCs). ► Single cell derived colonies of OSCCL express CSC-marker CD133 differentially. ► Monoclonal cell lines showed reduced sensitivity for Paclitaxel. ► In situ CD133+ cells are slow cycling (Ki67-) indicating a reduced drug sensitivity. ► CD133+ and CSC-like cells can be obtained from single colony forming cells of OSCCL.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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Cancer stem cell-like cells from a single cell of oral squamous carcinoma cell lines
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