| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1930907 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠NKp46 binds to heparin; however, other natural ligands for NKp46 have yet to be elucidated. ⺠We clarify the binding of NKp46-H6 to sulfate-containing glycans and sialyl Lewis X (sLeX). ⺠NKp46-H6 bound to multimeric sialyl Lewis X with a Kd value of 530 nM. ⺠Moreover, we investigated the putative glycan binding sites on NKp46 using mutants.
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Authors
Kenichiro Ito, Koji Higai, Mizuha Sakurai, Chihiro Shinoda, Kazuyuki Yanai, Yutaro Azuma, Kojiro Matsumoto,