Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1930953 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Insertion of a strong binding site for the MSL complex either upstream or at the 3Ⲡend of a reporter gene led to MSL complex binding and transcription upregulation in males. ⺠In contrast, gene transcription, binding site orientation and the local chromatin environment all appear to influence MSL complex binding to a weak site and transcription enhancement. ⺠Our results suggest that transcription enhancement in males requires a level of MSL complex binding above a certain threshold.
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Authors
Anja H. Schiemann, Vikki M. Weake, Fang Li, Corey Laverty, Esther J. Belikoff, Maxwell J. Scott,