| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1930972 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠A murine mAb to phosphoinositides neutralizes HIV-1 infection of cells in vitro. ⺠Neutralization occurred because of secretion of β-chemokines inhibitory to HIV-1. ⺠Secretion of β-chemokines was induced by the mAb even in the absence of HIV-1. ⺠Phosphoinositides are intracellular, thus the mAb may have exerted intracellular effects. ⺠A novel intracellular stimulation by a mAb of HIV-inhibitory chemokines is proposed.
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Authors
Gary R. Matyas, Lindsay Wieczorek, Divya Bansal, Agnes-Laurence Chenine, Eric Sanders-Buell, Sodsai Tovanabutra, Jerome H. Kim, Victoria Polonis, Carl R. Alving,