Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1931021 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Poly(n-butylcyano-acrylate) (PBCA) nanoparticles may be promising drug carriers. ⺠Influence of PBCA nanoparticles on the integrity of the blood-brain barrier in vitro. ⺠PBCA nanoparticles lead to a reversible disruption of the BBB in vitro after 4 h. ⺠Potential application as time-dependent and specific opener of the BBB.
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Authors
Ralf Rempe, Sandra Cramer, Sabine Hüwel, Hans-Joachim Galla,