| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1931460 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Tyk2 interacts with the proapoptotic protein Siva-1 via its N-terminus region. ⺠Tyk2 phosphorylates Siva-1, which has little effect on Siva-1-induced apoptosis. ⺠Tyk2 augments the apoptotic function of Siva-1 through the Tyk2-Siva-1 interaction.
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Authors
Haruko K. Shimoda, Kotaro Shide, Takuro Kameda, Takuya Matsunaga, Kazuya Shimoda,