Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1932797 | Biochemical and Biophysical Research Communications | 2009 | 5 Pages |
Abstract
The presence of neuropeptides and neuroreceptors in the bone have been reported in several studies. Bone turn-over seems to be controlled by the nervous system. The actual pathway or the control mechanism is still under investigation. In this study we investigate the changes in osteoblast cells if they are in co-culture with primary cortical brain cells. After seven days in co-culture with the primary fetal brain cells the osteoblast cells exhibited hypertrophic morphological changes and showed stronger ALP activity.
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Authors
Lucas Anissian, Michael Kirby, André Stark,