Article ID Journal Published Year Pages File Type
1933106 Biochemical and Biophysical Research Communications 2009 4 Pages PDF
Abstract

Fluorescent oligonucleotides provide useful way to study DNA during the sequencing-by-synthesis process. They allow researchers to determine the sequence of a short DNA strand. Fluorescence created by these chemicals must be removed after a few based pairs are read in order to continue reading the DNA sequence. Researchers have developed a variety of methods to solve this problem. This paper reviews the development of fluorescence removal in DNA sequencing and summarizes several methods of removing the fluorescence.

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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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