Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1933106 | Biochemical and Biophysical Research Communications | 2009 | 4 Pages |
Abstract
Fluorescent oligonucleotides provide useful way to study DNA during the sequencing-by-synthesis process. They allow researchers to determine the sequence of a short DNA strand. Fluorescence created by these chemicals must be removed after a few based pairs are read in order to continue reading the DNA sequence. Researchers have developed a variety of methods to solve this problem. This paper reviews the development of fluorescence removal in DNA sequencing and summarizes several methods of removing the fluorescence.
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Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Li Gao, Zuhong Lu,