Article ID Journal Published Year Pages File Type
1934044 Biochemical and Biophysical Research Communications 2009 6 Pages PDF
Abstract

The collection of gene deletion mutants of Saccharomyces cerevisiae was used to screen for novel genes required for UV-induced mutagenesis. We found the SBF transcription factor (Swi4/Swi6 protein complex) to be required for wild-type levels of UV mutability in forward and reverse mutation assays. Expression of translesion polymerase ζ component Rev7 was identified as a target of SBF-dependent regulation.

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