Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1934283 | Biochemical and Biophysical Research Communications | 2008 | 5 Pages |
Abstract
Cathepsin D is a normal and major component of lysosomes, it is found in almost all cells and tissues of mammals. Present review describes different events in cellular life of cathepsin D mainly its biosynthesis, co-translational and posttranslational modifications, targeting to lysosomes and proteolytic processing and maturation within lysosomes.
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Authors
Nousheen Zaidi, Andreas Maurer, Sebastian Nieke, Hubert Kalbacher,