Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1934832 | Biochemical and Biophysical Research Communications | 2008 | 4 Pages |
Abstract
Cathepsin E is an intracellular aspartic protease of the endolysosomal pathway. It has been implicated in several physiological and pathological processes however, its exact functional role is yet to be elucidated. The present review gives an account of the major physiological functions that are associated to cathepsin E by various research groups and highlights the conditions developed in cathepsin E deficiency or the conditions where overexpression of cathepsin E is observed.
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Authors
Nousheen Zaidi, Clemens Hermann, Timo Herrmann, Hubert Kalbacher,