Article ID Journal Published Year Pages File Type
1935310 Biochemical and Biophysical Research Communications 2008 4 Pages PDF
Abstract

IL-12 is an important type 1 immune activation cytokine. It is known that macrophages and dendritic cells the major cell types producing this cytokine and that these cells may release both the biologically inactive form (IL-12p40) and active form (IL-12p70) of IL-12. In this review, the latest information regarding the regulatory mechanisms governing the production of IL-12p70 by these cells is evaluated.

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