Article ID Journal Published Year Pages File Type
1935575 Biochemical and Biophysical Research Communications 2008 5 Pages PDF
Abstract
As a member of the corticotropin-releasing factor (CRF) family, urocortin (UCN) has been demonstrated to show diverse effects on cardiovascular system. It is commonly considered as a protective agent on vascular function. However, a growing body of evidence suggests that some effects of UCN may lead to endothelial dysfunction (ED) which may be the cause or consequence of vascular disease and a hallmark of known cardiovascular risk factors. The present review is then focused on recent evidence that reveals the beneficial and detrimental effects of UCN on endothelium.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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