| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1936632 | Biochemical and Biophysical Research Communications | 2007 | 5 Pages |
Abstract
To test the hypothesis that olfactory receptors (ORs) recognize different molecular features of odor molecules termed “odotypes”, we studied receptor–ligand interactions of two human and two mouse ORs, recognizing (−)citronellal. Structurally similar receptors provide identical binding pockets (OLFR43, OR1A1, and OR1A2), and have comparable EC50 values. Other ORs with lower sequence identity bind (−)citronellal in a different way, leading to different EC50 values.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Anna Stary, Chonticha Suwattanasophon, Peter Wolschann, Gerhard Buchbauer,