| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1936826 | Biochemical and Biophysical Research Communications | 2007 | 6 Pages |
Abstract
The role of mycothiol in mycobacteria was examined by comparative analysis of mutants disrupted in the four known genes encoding the protein machinery needed for mycothiol biosynthesis. These mutants were sensitive to acid stress, antibiotic stress, alkylating stress, and oxidative stress indicating that mycothiol and mycothiol-dependent enzymes protect the mycobacterial cell against attack from various different types of stresses and toxic agents.
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Authors
Mamta Rawat, Chantale Johnson, Vanessa Cadiz, Yossef Av-Gay,