| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1937478 | Biochemical and Biophysical Research Communications | 2007 | 6 Pages |
Abstract
Recently, neuroligins (NLs)3 and 4X have received much attention as autism-related genes. Here, we identified syntrophin-γ2 (SNTG2) as a de novo binding partner of NL3. SNTG2 also bound to NL4X and NL4Y. Interestingly, the binding was influenced by autism-related mutations, implying that the impaired interaction between NLs and SNTG2 contributes to the etiology of autism.
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Authors
Hidekuni Yamakawa, Satoko Oyama, Hiroaki Mitsuhashi, Noboru Sasagawa, Shigeo Uchino, Shinichi Kohsaka, Shoichi Ishiura,