Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1944343 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 9 Pages |
Abstract
⺠Ions neither follow distinct pathways nor bind specifically in VDAC wt and mutants. ⺠The pore region about half way the channel markedly influences VDAC selectivity. ⺠The charge distribution of the channel controls ion selectivity of the pore. ⺠The calculated ion selectivity is sensitive to slight conformational changes.
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Authors
Eva-Maria Krammer, Fabrice Homblé, Martine Prévost,