Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1944494 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
⺠We provide a synopsis of biophysical probes of membrane protein structure. ⺠We review the role of α-synuclein, a neuronal membrane-associated protein, in Parkinson's disease. ⺠We discuss the interactions of α-synuclein with model membranes and current structural models of the membrane-bound form. ⺠We present different mechanisms of how α-synuclein and membrane interactions are linked to Parkinson's disease.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Candace M. Pfefferkorn, Zhiping Jiang, Jennifer C. Lee,