| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 1944502 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠Reconstitution into native membrane-like environments is needed for quantitative biophysical studies of GPCRs. ⺠Six classes of membrane mimics are reviewed and evaluated for GPCR reconstitution. ⺠Classes reviewed here include micelles, bicelles, nanodiscs, lipid vesicles, planar lipid membranes, and lipidic cubic phases. ⺠Theoretical advantages and limitations for each reconstitution system are discussed. ⺠Examples of applications are provided.
Keywords
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Authors
Eugene Serebryany, Gefei Alex Zhu, Elsa C.Y. Yan,