Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1944530 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 6 Pages |
Abstract
⺠A significant inhibition in biotin uptake occurs upon mutating Cys294. ⺠The effect is not related to polar status of substituted cysteine residue. ⺠The inhibition is mediated via significant decrease in Vmax of the biotin uptake. ⺠Mutating Cys294 leads to a marked reduction in surface expression of hSMVT.
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Authors
Abhisek Ghosal, Hamid M. Said,