Article ID Journal Published Year Pages File Type
1944530 Biochimica et Biophysica Acta (BBA) - Biomembranes 2012 6 Pages PDF
Abstract
► A significant inhibition in biotin uptake occurs upon mutating Cys294. ► The effect is not related to polar status of substituted cysteine residue. ► The inhibition is mediated via significant decrease in Vmax of the biotin uptake. ► Mutating Cys294 leads to a marked reduction in surface expression of hSMVT.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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