Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1944532 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 8 Pages |
Abstract
⺠The release of different GPI-anchored proteins from the cell surface membrane is characterized in vitro and in vivo. ⺠GPI-anchors are cleaved and released into the cellular medium by phospholipase C. ⺠Phospholipase C isoforms discriminate between different GPI-proteins. ⺠Our data indicates that release of GPI-proteins by phospholipase C is fast, programmed and selective.
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Authors
Alexandra Müller, Christine Klöppel, Megan Smith-Valentine, Judith Van Houten, Martin Simon,