Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1945057 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2009 | 10 Pages |
Abstract
Glycosphingolipids, due to their tendency to form laterally separated liquid-ordered phases, possess a high potential for the creation of order in biological membranes. The formation of glycosphingolipid-rich domains within the membrane has profound consequences on the membrane organization at different levels, and on the conformational and biological properties of membrane-associated proteins and multimolecular protein complexes. In this review, we will discuss 1) how glycosphingolipids influence the lateral organization of biological membranes; 2) how glycosphingolipids influence the function of membrane-associated proteins.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Alessandro Prinetti, Nicoletta Loberto, Vanna Chigorno, Sandro Sonnino,