Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1945215 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2009 | 8 Pages |
Abstract
Epithelial and endothelial tight junctions act as a rate-limiting barrier between an organism and its environment. Continuing studies have highlighted the regulation of the tight junction barrier by cytokines. Elucidation of this interplay is vital for both the understanding of physiological tight junction regulation and the etiology of pathological conditions. This review will focus on recent advances in our understanding of the molecular mechanisms of tight junctions modulation by cytokines.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Christopher T. Capaldo, Asma Nusrat,