Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
1946539 | Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms | 2012 | 6 Pages |
Genome organization into nucleosomes and higher-order chromatin structures has profound implications for the regulation of gene expression, DNA replication and repair. The structure of chromatin can be remodeled by several mechanisms; among others, nucleosome assembly/disassembly and replacement of canonical histones with histone variants constitute important ones. In this review, we provide a brief description on the current knowledge about histone chaperones involved in nucleosome assembly/disassembly and histone variants in Arabidopsis thaliana. We discuss recent advances in revealing crucial functions of histone chaperones, nucleosome assembly/disassembly and histone variants in plant response to abiotic stresses. It appears that chromatin structure remodeling may provide a flexible, global and stable means for the regulation of gene transcription to help plants more effectively cope with environmental stresses. This article is part of a Special Issue entitled: Histone chaperones and chromatin assembly.
► Histone variants and nucleosome assembly. ► Genotoxic stress and genome stability. ► Stress-induced transcription and modifications of nucleosome occupancy and histone variant incorporation.